Activation of Ca2+-activated Cl− channels (CaCCs/Anoctamine)
Description
Calcium-activated chloride channels open due to increases in the cytosolic concentration of Ca2+. This template shows that sources of calcium that can activate these channels. They also show that chlorine can flow in both directions depending on its equilibrium potential.
Acknowledgements
References
TMEM16A Protein: A New Identity for Ca2+-Dependent Cl− Channels
Loretta Ferrera, Antonella Caputo, and Luis J. V. Galietta
Physiology 2010 25:6, 357-363
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