A Nanoprimer to Improve the Systemic Delivery of siRNA and mRNA
Description
This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication.
The injection of a nanoprimer that occupies liver cells transiently, before the injection of lipid nanoparticles (LNPs) encapsulating RNA, leads to an improved biodistribution and a more efficient in vivo delivery.
Acknowledgements
References
Nell R. M. Saunders, Marion S. Paolini et al. A Nanoprimer To Improve the Systemic Delivery of siRNA and mRNA. Nano Lett. 20, 6, 4264–4269 (2020). 10.1021/acs.nanolett.0c00752
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