Non-Phagocytic Nanoparticle Internalization Pathways

Description

This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication. This figure depicts the three major non-phagocytic cellular internalization pathways of nanoparticles (NPs): macropinocytosis, clathrin-mediated endocytosis and caveolae-mediated endocytosis. The first two pathways generally lead to lysosomal degradation, while NPs entered via caveolae-mediated pathway can sometimes escape fusion with lysosome. Therefore, designing NPs to enter through caveolae-mediated pathway can increase the chances of successful drug delivery.

Acknowledgements

References

Behzadi, Shahed et. al. (2017) Cellular uptake of nanoparticles: journey inside the cell. Chemical Society Reviews. https://pubs.rsc.org/en/content/articlelanding/2017/cs/c6cs00636a

Get started with this template for free

Don’t start from scratch.

Create professional scientific illustrations quickly and easily, even without any design expertise

Get started with a huge library of editable icons and templates such as common biological pathways, anatomy, or genetics.
Create figures that effectively communicate your research in half the time using our editable icons.
Use our PDB tool to quickly generate and customize protein structures

Get started now