Blimp-1 is Essential for Allergen-Induced Asthma and Th2 Development in the Lung
Description
This template was adapted from the original submission. Edits were made to enhance scientific accuracy, optimal usability and/or to meet industry-leading design standards for science communication.
The transcriptional repressor Blimp-1, known to constrain autoimmunity, is an unexpected and critical positive regulator of Th2 cells in the lung acting via an IL-10-STAT3 axis in response to inhaled allergens, driving pathophysiology associated with asthma disease.
Acknowledgements
References
Kun He. (2020) Blimp-1 is essential for allergen-induced asthma and Th2 development in the lung. The Journal of Experimental Medicine.
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